Vivamer has developed a range of polymer backbones that have been designed to react to environmental triggers, e.g. pH change, light or temperature. The responsive polymers act as a chemical switch, activating or releasing a payload agent in response to the environmental stimulus. Polymer chemistries have been synthesized that will react within a series of narrowly defined pH windows, or specific wavelengths of light. The switching event is achieved by causing the polymers to change their conformation.
The responsive polymers can be deployed in a range of polymer formats, providing Vivamer's partners with a number of product design options, including soluble conjugates, encapsulated nano-particles, responsive films and implants.
Vivamer’s responsive polymer technology can be used to develop imaging agents with:
